Table of Contents

1. Introduction
2. What is Daptomycin?
3. Do You Need a Prescription for Daptomycin?
4. How Does Daptomycin Work?
5. What Are the Common Side Effects of Daptomycin?
6. What Should You Not Take with Daptomycin?
7. Coupons and Copay Information

Introduction

Daptomycin is an antibiotic drug used to treat a variety of bacterial infections, including skin and soft tissue infections, bone and joint infections, and bacterial endocarditis. It is a relatively new drug, first approved by the U.S. Food and Drug Administration (FDA) in 2003. It is available in both intravenous (IV) and oral forms. In this article, we will discuss daptomycin prices, coupons, copay information, and medication guide.

What is Daptomycin?

Daptomycin is a lipopeptide antibiotic that works by interfering with the cell wall of bacteria, causing them to rupture and die. It is used to treat a variety of bacterial infections, including skin and soft tissue infections, bone and joint infections, and bacterial endocarditis. It is most effective against Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae. It is not effective against Gram-negative bacteria.

Do You Need a Prescription for Daptomycin?

Yes, daptomycin is a prescription drug and must be prescribed by a doctor. It is available in both intravenous (IV) and oral forms. The IV form is usually administered in a hospital setting, while the oral form is taken at home.

How Does Daptomycin Work?

Daptomycin works by interfering with the cell wall of bacteria, causing them to rupture and die. It is most effective against Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae. It is not effective against Gram-negative bacteria.

Daptomycin works by binding to the cell wall of bacteria, causing the cell wall to become unstable and rupture. This process is known as “lysis”. The drug works best when given in high doses, as this allows it to bind to more bacteria and cause more cells to rupture.

What Are the Common Side Effects of Daptomycin?

The most common side effects of daptomycin include nausea, vomiting, diarrhea, headache, and rash. Less common side effects include dizziness, fever, chills, and joint pain. Rare side effects include anemia, low white blood cell count, and liver damage.

What Should You Not Take with Daptomycin?

You should not take daptomycin with other antibiotics, as this can increase the risk of side effects. You should also avoid taking daptomycin with anticoagulants, as this can increase the risk of bleeding.

Coupons and Copay Information

Daptomycin is usually covered by most insurance plans. However, some plans may require you to pay a copay or coinsurance. You may also be able to find coupons or discounts for daptomycin online.

Indications for Daptomycin

Daptomycin is an antibiotic used to treat certain types of bacterial infections. It is indicated for the treatment of complicated skin and skin structure infections (cSSSI) caused by susceptible Staphylococcus aureus, including methicillin-resistant strains (MRSA), Streptococcus pyogenes, Streptococcus agalactiae, and Enterococcus faecalis (vancomycin-susceptible strains). It is also indicated for the treatment of bacteremia, including right-sided infective endocarditis, caused by susceptible S. aureus (including MRSA) and Enterococcus faecalis (vancomycin-susceptible strains).

Dosage and Administration Recommendations

The recommended dosage of daptomycin for the treatment of cSSSI is 4 mg/kg once daily as an intravenous (IV) infusion over 30 to 120 minutes. For the treatment of bacteremia, the recommended dosage is 6 mg/kg once daily as an IV infusion over 30 to 120 minutes. Daptomycin should be administered as a single daily dose and should not be administered as an intermittent infusion. Daptomycin should be administered after hemodialysis or continuous renal replacement therapy (CRRT).

Common Drug Interactions

Daptomycin should be used with caution in patients who are taking other medications that may interact with it. It is important to tell your healthcare provider about all medications you are taking, including over-the-counter medications, vitamins, and herbal supplements. Some medications that may interact with daptomycin include anticoagulants, antifungals, and certain antibiotics.

Warnings for this Drug

Daptomycin should not be used in patients with a known hypersensitivity to the drug or its components. It should also not be used in patients with myopathy or elevated serum creatine kinase levels. It is important to tell your healthcare provider if you have any of these conditions before starting treatment with daptomycin.

Clinical Pharmacology

Daptomycin is a lipopeptide antibiotic that works by disrupting the bacterial cell membrane. It is active against a wide range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is rapidly bactericidal and has a high affinity for the cell membrane. It is mainly excreted unchanged in the urine and has a half-life of approximately 4 hours.

Medication Guide

Daptomycin is an antibiotic used to treat certain types of bacterial infections. It is important to take daptomycin exactly as prescribed by your healthcare provider. Do not take more or less than the recommended amount or for a longer or shorter period of time than prescribed. It is important to tell your healthcare provider about all medications you are taking, including over-the-counter medications, vitamins, and herbal supplements. Do not stop taking daptomycin or change your dose without talking to your healthcare provider first.

Conclusion

Daptomycin is an effective antibiotic used to treat certain types of bacterial infections. It is important to take daptomycin exactly as prescribed and to tell your healthcare provider about all medications you are taking. It is also important to be aware of the potential drug interactions and warnings associated with daptomycin. With careful monitoring and proper use, daptomycin can be an effective treatment for bacterial infections.

Sources:

1. U.S. National Library of Medicine. Daptomycin. https://www.ncbi.nlm.nih.gov/books/NBK539077/
2. U.S. National Library of Medicine. Daptomycin: Drug Information. https://www.ncbi.nlm.nih.gov/books/NBK539077/